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Deep models of integrated multiscale molecular data decipher the endothelial cell response to ionizing radiation

Ian Morilla , Philippe Chan , Fanny Caffin , Ljubica Svilar , Sonia Selbonne , et al.
iScience, 2022, 25, pp.103685. ⟨10.1016/j.isci.2021.103685⟩
Article dans une revue hal-03605168v1
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Targeted nuclear irradiation with a proton microbeam induces oxidative DNA base damage and triggers the recruitment of DNA glycosylases OGG1 and NTH1

Elena Robeska , Kevin Lalanne , François Vianna-Legros , Haser Hasan Sutcu , Andriy Khobta , et al.
DNA Repair, 2024, 133, pp.103610. ⟨10.1016/j.dnarep.2023.103610⟩
Article dans une revue hal-04324425v1
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Radiobiologie des très fortes doses par fraction: connaissances en 2020 et nouvelles modélisations précliniques.

Annaïg Bertho , Morgane dos Santos , Agnes Francois , Fabien Milliat
Radioprotection, 2020, 56 (1), pp.11-24. ⟨10.1051/radiopro/2020072⟩
Article dans une revue hal-03167221v1
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Use of omics analysis for low-dose radiotoxicology and health risk assessment: the case of uranium

Stéphane Grison , Maamar Souidi
Environmental Epigenetics, 2022, 8 (1), pp.1-7. ⟨10.1093/eep/dvac025⟩
Article dans une revue irsn-04021256v1
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Global microRNA profiling uncovers miR-206 as a negative regulator of hematopoietic commitment in human pluripotent stem cells

S. Flamant , J.-C. Chomel , C. Desterke , O. Féraud , E. Gobbo , et al.
International Journal of Molecular Sciences, 2019, 20 (7), pp.1737. ⟨10.3390/ijms20071737⟩
Article dans une revue hal-02524209v1
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Histoire de la prise en charge des cancers broncho-pulmonaires non à petites cellules de stade précoce : de la chirurgie à la radiothérapie stéréotaxique

Annaig Bertho , Morgane dos Santos , Agnes Francois , Fabien Milliat
Radioprotection, 2020, 55 (3), pp.165-172. ⟨10.1051/radiopro/2020050⟩
Article dans une revue hal-03167222v1
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Transmission of persistent ionizing radiation-induced foci through cell division in human primary cells

Aurelie Vaurijoux , Pascale Voisin , Amélie Freneau , Joan Francesc Barquinero , Gaetan Gruel
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 2017, 797-799, pp.15-25. ⟨10.1016/j.mrfmmm.2017.03.003⟩
Article dans une revue hal-02457234v1

Impact and consequences of DNA damage on skeletal muscle cells

Haser Sutcu , Francois Vianna-Legros , Celine Baldeyron
Responses to DNA damage -the 11th quinquennial conference on DNA repair, Apr 2022, EGMOND AAN ZEE, Netherlands
Communication dans un congrès irsn-03630641v1
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Inflammatory cells dynamics control neovascularization and tissue healing after localized radiation induced injury in mice

Celine Loinard , Mohamed‐amine Benadjaoud , Bruno L'Homme , Stephane Flamant , Jan Baijer , et al.
Communications Biology, 2023, 6 (571), ⟨10.1038/s42003-023-04939-3⟩
Article dans une revue irsn-04251633v1
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Biological measure of DNA damage after single-ion microbeam irradiation and Monte Carlo simulations

Geraldine Gonon , Carmen Villagrasa , Pascale Voisin , Sylvain Meylan , Mohamedamine Benadjaoud , et al.
16th International Congress of Radiation Research ICRR 2019, Aug 2019, MANCHESTER, France. 2019
Poster de conférence hal-02635559v1
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Importance of dosimetry protocol for cell irradiation on a low X-rays facility and consequences for the biological response

Morgane dos Santos , Vincent Paget , Mariam Ben Kacem , Francois Trompier , Mohamedamine Benadjaoud , et al.
International Journal of Radiation Biology, 2018, 94 (6), pp.597-606. ⟨10.1080/09553002.2018.1466205⟩
Article dans une revue hal-02457228v1
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Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

Amelie Schellenbauer , Marie-Noelle Guilly , Romain Grall , Romain Le bars , Vincent Paget , et al.
Nucleic Acids Research, 2021, 49 (20), pp.11728-11745. ⟨10.1093/nar/gkab980⟩
Article dans une revue hal-03424945v1
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HGF and TSG-6 Released by Mesenchymal Stem Cells Attenuate Colon Radiation-Induced Fibrosis

Benoit Usunier , Clement Brossard , Bruno L Homme , Christine Linard , Marc Benderitter , et al.
International Journal of Molecular Sciences, 2021, 22 (4), pp.1790. ⟨10.3390/ijms22041790⟩
Article dans une revue hal-03157083v1

Cellular therapy treatment of chronic radiation cystitis in rats

Clement Brossard , Morgane dos Santos , Mohamedamine Benadjaoud , Christelle Demarquay , Valerie Buard , et al.
17th Annual International Federation for Adipose Therapeutics and Sciences Conference, IFATS 2019, Dec 2019, MARSEILLE, France
Communication dans un congrès hal-03447873v1
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Development of whole brain versus targeted dentate gyrus irradiation model to explain low to moderate doses of exposure effects in mice

Morgane dos Santos , Dimitri Kereselidze , Celine Gloaguen , Mohamedamine Benadjaoud , Karine Tack , et al.
Scientific Reports, 2018, 8 (1), pp.17262. ⟨10.1038/s41598-018-35579-x⟩
Article dans une revue hal-02443070v1
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Applying a multiscale systems biology approach to study the effect of chronic low-dose exposure to uranium in rat kidneys

Stephane Grison , Dimitri Kereselidze , David Cohen , Celine Gloaguen , Christelle Elie , et al.
International Journal of Radiation Biology, 2019, 95 (6), pp.737-752. ⟨10.1080/09553002.2019.1577567⟩
Article dans une revue hal-02457223v1

Preclinical study of chronic radiation cystitis and cell therapy treatment

Clement Brossard , Anne-Chalotte Lefranc , Morgane dos Santos , Mohamedamine Benadjaoud , Christelle Demarquay , et al.
ESTRO, ESTRO, Aug 2021, MADRID, Spain
Communication dans un congrès hal-03536394v1
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RENEB Inter-Laboratory Comparison 2021: The Dicentric Chromosome Assay

D. Endesfelder , U. Oestreicher , M. Bucher , C. Beinke , C Siebenwirth , et al.
Radiation Research, 2023, 199 (6), pp.556-570. ⟨10.1667/RADE-22-00202.1⟩
Article dans une revue irsn-04243665v1
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From Energy Deposition of Ionizing Radiation to Cell Damage Signaling: Benchmarking Simulations by Measured Yields of Initial DNA Damage after Ion Microbeam Irradiation

Geraldine Gonon , Carmen Villagrasa , Pascale Voisin , Sylvain Meylan , Marta Bueno Vizcarra , et al.
Radiation Research, 2019, 191 (6), pp.566-584. ⟨10.1667/RR15312.1⟩
Article dans une revue hal-02318865v1
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Minimum Reporting Standards Should be Expected for Preclinical Radiobiology Irradiators and Dosimetry in the Published Literature

Yannick Poirier , Larry Dewerd , François Trompier , Morgane dos Santos , Ke Sheng , et al.
Radiation Research, 2023, 200 (3), pp.217-222. ⟨10.1667/RADE-23-00119.1⟩
Article dans une revue irsn-04207658v1
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Dosimetry for cell irradiation using orthovoltage (40-300 kv) x-ray facilities

Morgane dos Santos , Vincent Paget , Francois Trompier , Gaetan Gruel , Fabien Milliat
Journal of visualized experiments : JoVE, 2021, 2021 (168), pp.e61645. ⟨10.3791/61645⟩
Article dans une revue hal-03207090v1
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RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay

David Endesfelder , Ursula Oestreicher , Ulrike Kulka , Elizabeth Ainsbury , Jayne Moquet , et al.
International Journal of Radiation Biology, 2021, 97 (9), pp.1181 - 1198. ⟨10.1080/09553002.2021.1941380⟩
Article dans une revue hal-03354887v1
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Machine learning and convolutional networks for an augmented expertise in biological dosimetry

Antonin Deschemps
Machine Learning [stat.ML]. Université Rennes 1, 2023. English. ⟨NNT : ⟩
Thèse tel-04466974v1
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Étude des conséquences génétiques et épigénétiques consécutives à la signalisation persistante des dommages radio-induits de l'ADN

Aurélie Vaurijoux
Biologie cellulaire. Université Paris Saclay (COmUE), 2016. Français. ⟨NNT : 2016SACLS515⟩
Thèse tel-01500100v1
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Decline of DNA damage response along with myogenic differentiation

Haser H Sutcu , Phoebe Rassinoux , Lise-Marie Donnio , Damien Neuillet , François Vianna-Legros , et al.
Life Science Alliance, 2023, 7 (2), pp.e202302279. ⟨10.26508/lsa.202302279⟩
Article dans une revue hal-04302036v2

Retrospective dosimetry 22 years later: a case report

Juan S Martinez , Delphine Dugue , Pascale Fernandez , Eric Gregoire , Gaëtan Gruel
EPR BioDose Paris 2022, IABERD, Jun 2022, Fontenay aux Roses, France
Communication dans un congrès irsn-03955509v1
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Variation of 4 MV X-ray dose rate strongly impacts biological response both in vitro and in vivo

Mariam Ben Kacem , Mohamedamine Benadjaoud , Morgane dos Santos , Frédéric Soysouvanh , Valerie Buard , et al.
Scientific Reports, 2020, 10, pp.64067-4. ⟨10.1038/s41598-020-64067-4⟩
Article dans une revue hal-02869301v1
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Multiparametric radiobiological assays show that variation of X-ray energy strongly impacts relative biological effectiveness: comparison between 220 kV and 4 MV

Vincent Paget , Mariam Ben Kacem , Morgane dos Santos , Mohamed Amine Benadjaoud , Frédéric Soysouvanh , et al.
Scientific Reports, 2019, 9, pp.14328. ⟨10.1038/s41598-019-50908-4⟩
Article dans une revue hal-02345044v1
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Variation of 4 MV X-ray dose rate in fractionated irradiation strongly impacts biological endothelial cell response in vitro

Mariam Ben Kacem , Mohamedamine Benadjaoud , Morgane dos Santos , Valerie Buard , Georges Tarlet , et al.
International Journal of Radiation Biology, 2022, 98 (1), pp.50-59. ⟨10.1080/09553002.2022.1998703⟩
Article dans une revue hal-03520211v1

Preclinical study of Chronic radiation cystitis and cell therapy treatment

Clement Brossard , Anne-Chalotte Lefranc , Morgane dos Santos , Mohamedamine Benadjaoud , Christelle Demarquay , et al.
5th International Military Radiation and Innovation Symposium, IMRIS 2020, Oct 2020, PARIS, France
Communication dans un congrès hal-03437410v1