Cyclic AMP synthesis and hydrolysis in the normal and failing heart, Pflug. Arch, vol.466, pp.1163-1177, 2014. ,
Adrenergic signaling in heart failure: A balance of toxic and protective effects, Pflug. Arch, vol.466, pp.1139-1150, 2014. ,
Mechanisms of protein kinase A anchoring, Int. Rev. Cell Mol. Biol, vol.283, pp.235-330, 2010. ,
?-adrenergic receptor signalling and its functional consequences in the diseased heart, Eur. J. Clin. Investig, vol.46, pp.362-374, 2016. ,
Regulation of cardiac Na + -Ca 2+ exchanger activity by protein kinase phosphorylation-Still a paradox? Cell Calcium, vol.45, pp.1-10, 2009. ,
Depressed PKA activity contributes to impaired SERCA function and is linked to the pathogenesis of glucose-induced cardiomyopathy, J. Mol. Cell. Cardiol, vol.34, pp.985-996, 2002. ,
Compartmentalization role of A-kinase anchoring proteins (AKAPs) in mediating protein kinase A (PKA) signaling and cardiomyocyte hypertrophy, Int. J. Mol. Sci, vol.16, pp.218-229, 2015. ,
Ketamine inhibits the proinflammatory cytokine-induced reduction of cardiac intracellular cAMP accumulation, Anesth. Analg, vol.87, pp.1015-1019, 1998. ,
Impairment of cardiac ?-adrenoceptor cellular signaling by decreased expression of G(s ?) in septic rabbits, Anesthesiology, vol.93, pp.1465-1473, 2000. ,
Desensitization of rat cardiomyocyte adenylyl cyclase stimulation by plasma of noradrenaline-treated patients with septic shock, Circ. Shock, vol.41, pp.48-59, 1993. ,
Cellular energetic metabolism in sepsis: The need for a systems approach, Biochim. Biophys. Acta, vol.1777, pp.763-771, 2008. ,
Carbon monoxide rescues mice from lethal sepsis by supporting mitochondrial energetic metabolism and activating mitochondrial biogenesis, J. Pharmacol. Exp. Ther, vol.329, pp.641-648, 2009. ,
Inhibition of mitochondrial permeability transition prevents sepsis-induced myocardial dysfunction and mortality, J. Am. Coll. Cardiol, vol.48, pp.377-385, 2006. ,
Role of soluble adenylyl cyclase in mitochondria, Biochim. Biophys. Acta, vol.1842, pp.2555-2560, 2014. ,
, Physiology, vol.28, pp.199-209, 2013.
Cyclic AMP produced inside mitochondria regulates oxidative phosphorylation, Cell Metab, vol.9, pp.265-276, 2009. ,
The inner and outer compartments of mitochondria are sites of distinct cAMP/PKA signaling dynamics, J. Cell Biol, vol.202, pp.453-462, 2013. ,
Regulation of mitochondrial oxidative phosphorylation through cell signaling, Biochim. Biophys. Acta, vol.1773, pp.1701-1720, 2007. ,
Activation of the cAMP cascade in human fibroblast cultures rescues the activity of oxidatively damaged complex I. Free Radic, Biol. Med, vol.52, pp.757-764, 2012. ,
Regulation of mitochondrial respiration and apoptosis through cell signaling: Cytochrome c oxidase and cytochrome c in ischemia/reperfusion injury and inflammation, Biochim. Biophys. Acta, vol.1817, pp.598-609, 2012. ,
Energy crisis: The role of oxidative phosphorylation in acute inflammation and sepsis, Biochim. Biophys. Acta, vol.1842, pp.1579-1586, 2014. ,
Analysis of mitochondrial function in situ in permeabilized muscle fibers; tissues and cells, Nat. Protoc, vol.3, pp.965-976, 2008. ,
Protein phosphorylation and prevention of cytochrome oxidase inhibition by ATP: Coupled mechanisms of energy metabolism regulation, Cell Metab, vol.13, pp.712-719, 2011. ,
A phosphodiesterase 2A isoform localized to mitochondria regulates respiration, J. Biol. Chem, vol.286, pp.30423-30432, 2011. ,
Mechanisms of sepsis-induced cardiac dysfunction, Crit. Care Med, vol.35, pp.1599-1608, 2007. ,
Cecal ligation and puncture sepsis is associated with attenuated expression of adenylyl cyclase 9 and increased miR142-3p, Shock, vol.36, pp.390-395, 2011. ,
Lipopolysaccharide attenuates mRNA levels of several adenylyl cyclase isoforms in vivo, Biochim. Biophys. Acta, vol.1772, pp.32-39, 2007. ,
Atorvastatin prevents sepsis-induced downregulation of myocardial beta1-adrenoceptors and decreased cAMP response in mice, Shock, vol.41, pp.406-412, 2014. ,
Early functional and transcriptomic changes in the myocardium predict outcome in a long-term rat model of sepsis, Clin. Sci, vol.124, pp.391-401, 2013. ,
The many faces of H89: A review, Cardiovasc. Drug Rev, vol.24, pp.261-274, 2006. ,
Caffeine restores myocardial cytochrome oxidase activity and improves cardiac function during sepsis, Crit. Care Med, vol.37, pp.1397-1402, 2009. ,
Cilostazol protects mice against endotoxin shock and attenuates LPS-induced cytokine expression in RAW 264.7 macrophages via MAPK inhibition and NF-?B inactivation: Not involved in cAMP mechanisms, Int. Immunopharmacol, vol.10, pp.1077-1085, 2010. ,
Phosphodiesterase 4 inhibition dose dependently stabilizes microvascular barrier functions and microcirculation in a rodent model of polymicrobial sepsis, Shock, vol.41, pp.537-545, 2014. ,
LPS-induced acute lung injury is attenuated by phosphodiesterase inhibition: Effects on proinflammatory mediators; metallo proteinases; NF-?B; and ICAM-1 expression, J. Trauma, vol.60, pp.115-125, 2006. ,
Sildenafil citrate concentrations not affecting oxidative phosphorylation depress H 2 O 2 generation by rat heart mitochondria, Mol. Cell. Biochem, vol.309, pp.77-85, 2008. ,
, Int. J. Mol. Sci, vol.17, p.2075, 2016.
Phosphodiesterase 2A is a major negative regulator of iNOS expression in lipopolysaccharide-treated mouse alveolar macrophages, J. Leukoc. Biol, vol.96, pp.907-915, 2014. ,
Impaired heart rate regulation and depression of cardiac chronotropic and dromotropic function in polymicrobial sepsis, Shock, vol.43, pp.185-191, 2015. ,
A robust scoring system to evaluate sepsis severity in an animal model, BMC Res. Notes, 2014. ,