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Article Dans Une Revue Brain Stimulation Année : 2019

Psychogenic non-epileptic seizures treated with guided transcranial direct current stimulation: a case report

Résumé

Psychogenic non-epileptic seizures (PNES) are paroxysms of either altered subjective or objective manifestations that may mimic epileptic seizures (ES), without abnormal neuronal epileptiform activity. In this report, we present the case of a 39-year-old woman with PNES and functional movement disorders, who was successfully treated with neuro-guided transcranial direct current stimulation (tDCS). We used a PET-guided tDCS approach, as a hypometabolism of the frontal region was revealed by FDG TEP scan. TDCs was performed 5 days/week, 2 times/day, during 3 weeks. All clinical manifestations were reported in a seizure diary. We also assessed dissociation, depression, alexithymia, psychotraumatic scales, and involuntary movements. The treatment was followed by a decrease of both psychogenic involuntary movements and PNES at 5 weeks. At the same time, PTSD symptoms, dissociative symptoms, depression and alexithymia improved. PET-scan and tDCS seems to be promising tools for the evaluation and treatment of PNES in clinical practice, and may have a specific role on dissociative symptoms.

Dates et versions

hal-02534716 , version 1 (07-04-2020)

Identifiants

Citer

Arnaud Leroy, Martin Beigne, Gregory Petyt, Philippe Derambure, Guillaume Vaiva, et al.. Psychogenic non-epileptic seizures treated with guided transcranial direct current stimulation: a case report. Brain Stimulation, 2019, Brain stimulation, 12 (3), pp.794-796. ⟨10.1016/j.brs.2019.01.019⟩. ⟨hal-02534716⟩
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