R. A. Payne, A. J. Avery, M. Duerden, C. L. Saunders, C. R. Simpson et al., Prevalence of polypharmacy in a Scottish primary care population, Eur J Clin Pharmacol, vol.70, pp.575-81, 2014.

B. Hovstadius, K. Hovstadius, B. Astrand, and G. Petersson, Increasing polypharmacy -an individual-based study of the Swedish population, BMC Clin Pharmacol, vol.10, p.16, 2005.

M. Pirmohamed, S. James, S. Meakin, C. Green, A. K. Scott et al., Adverse drug reactions as cause of admission to hospital: prospective analysis of 18 820 patients, BMJ, vol.329, pp.15-24, 2004.

J. Ma, Y. Wang, M. Gao, Q. Meng, and J. Liu, Adverse drug reactions as the cause of emergency department admission of patients aged 80 years and older, Eur J Intern Med, vol.23, pp.162-165, 2012.

A. Conforti, D. Costantini, F. Zanetti, U. Moretti, M. Grezzana et al., Adverse drug reactions in older patients: an Italian observational prospective hospital study. Drug Health Patient Safe, vol.4, pp.75-80, 2012.

C. Kongkaew, P. R. Noyce, and D. M. Ashcroft, Hospital admissions associated with adverse drug reactions: a systematic review of prospective observational studies, Ann Pharmacother, vol.42, pp.1017-1042, 2008.

S. M. Patterson, C. A. Cadogan, N. Kerse, C. R. Cardwell, M. C. Bradley et al., Interventions to improve the appropriate use of polypharmacy for older people, Cochrane Database Syst. Rev

J. Wiley, &. Sons, and ;. Ltd, , 2014.

A. D. Meid, A. Lampert, A. Burnett, H. M. Seidling, and W. E. Haefeli, The impact of pharmaceutical care interventions for medication underuse in older people: a systematic review and meta-analysis, Br J Clin Pharmacol, vol.80, pp.768-76, 2015.

E. C. Lehnbom, M. J. Stewart, E. Manias, and J. I. Westbrook, Impact of medication reconciliation and review on clinical outcomes, Ann Pharmacother, vol.48, pp.1298-312, 2014.

E. Hatah, R. Braund, J. Tordoff, and S. B. Duffull, A systematic review and metaanalysis of pharmacist-led fee-for-services medication review, Br J Clin Pharmacol, vol.77, pp.102-117, 2014.

M. Christensen and A. Lundh, Medication review in hospitalised patients to reduce morbidity and mortality, Cochrane Database Syst Rev, vol.2, p.8986, 2016.

T. Graabaek and L. J. Kjeldsen, Medication reviews by clinical pharmacists at hospitals lead to improved patient outcomes: a systematic review, Basic Clin Pharmacol Toxicol, vol.112, pp.359-73, 2013.

L. Forsetlund, M. C. Eike, E. Gjerberg, and G. E. Vist, Effect of interventions to reduce potentially inappropriate use of drugs in nursing homes: a systematic review of randomised controlled trials, BMC Geriatr, vol.11, p.16, 2011.

S. M. Wallerstedt, J. M. Kindblom, K. Nylén, O. Samuelsson, and A. Strandell, Medication reviews for nursing home residents to reduce mortality and hospitalization: systematic review and meta-analysis, Br J Clin Pharmacol, vol.78, pp.488-97, 2014.

R. Thomas, A. L. Huntley, M. Mann, D. Huws, G. Elwyn et al., Pharmacist-led interventions to reduce unplanned admissions for older people: a systematic review and meta-analysis of randomised controlled trials, Age Ageing, vol.43, pp.174-87, 2014.

R. Holland, J. Desborough, L. Goodyer, S. Hall, D. Wright et al., Does pharmacist-led medication review help to reduce hospital admissions and deaths in older people? A systematic review and meta-analysis, Br J Clin Pharmacol, vol.65, pp.303-319, 2008.

D. P. Alldred, M. Kennedy, C. Hughes, T. F. Chen, and P. Miller, Interventions to optimise prescribing for older people in care homes, Cochrane Database Syst. Rev

J. Wiley, &. Sons, and ;. Ltd, , 2016.

M. Geurts, J. Talsma, J. Brouwers, and J. J. De-gier, Medication review and reconciliation with cooperation between pharmacist and general practitioner and the benefit for the patient: a systematic review, Br J Clin Pharmacol, vol.74, pp.16-33, 2012.

M. Viswanathan, L. C. Kahwati, C. E. Golin, S. J. Blalock, E. Coker-schwimmer et al., Medication therapy management interventions in outpatient settings: a systematic review and meta-analysis, JAMA Intern Med, vol.175, pp.76-87, 2015.

C. M. Hohl, M. E. Wickham, B. Sobolev, J. J. Perry, M. Sivilotti et al., The effect of early in-hospital medication review on health outcomes: a systematic review, Br J Clin Pharmacol, vol.80, pp.51-61, 2015.

P. R. Williamson, D. G. Altman, J. M. Blazeby, M. Clarke, D. Devane et al., Developing core outcome sets for clinical trials: issues to consider, Trials, vol.13, p.132, 2012.

L. Idzerda, T. Rader, P. Tugwell, and M. Boers, Can we decide which outcomes should be measured in every clinical trial? A scoping review of the existing conceptual frameworks and processes to develop core outcome sets, J Rheumatol, vol.41, pp.986-93, 2014.

J. J. Kirkham, E. Gargon, M. Clarke, and P. R. Williamson, Can a core outcome set improve the quality of systematic reviews?-a survey of the Co-ordinating Editors, Cochrane Review Groups. Trials, vol.14, p.21, 2013.

J. J. Kirkham, K. M. Dwan, D. G. Altman, C. Gamble, S. Dodd et al., The impact of outcome reporting bias in randomised controlled trials on a cohort of systematic reviews, BMJ, vol.340, p.365, 2010.

B. Hart, A. Lundh, and L. Bero, Effect of reporting bias on meta-analyses of drug trials: reanalysis of meta-analyses, BMJ, vol.344, p.7202, 2012.

M. J. Page, J. E. Mckenzie, J. Kirkham, K. Dwan, S. Kramer et al., Bias due to selective inclusion and reporting of outcomes and analyses in systematic reviews of randomised trials of healthcare interventions, Cochrane Database Syst Rev, vol.10, p.35, 2014.

D. M. Zulman, J. B. Sussman, X. Chen, C. T. Cigolle, C. S. Blaum et al., Examining the evidence: a systematic review of the inclusion and analysis of older adults in randomized controlled trials, J Gen Intern Med, vol.26, pp.783-90, 2011.

A. Cherubini, D. Signore, S. Ouslander, J. Semla, T. Michel et al., Fighting against age discrimination in clinical trials, J Am Geriatr Soc, vol.58, pp.1791-1797, 2010.

M. Boers, J. R. Kirwan, G. Wells, D. Beaton, L. Gossec et al., Developing core outcome measurement sets for clinical trials: OMERACT Filter 2.0, J Clin Epidemiol, vol.67, pp.745-53, 2014.

J. J. Kirkham, S. Gorst, D. G. Altman, J. M. Blazeby, M. Clarke et al., Core Outcome Set-STAndards for Reporting: the COS-STAR Statement, PLoS Med, vol.13, 2016.

J. Beuscart, O. Dalleur, B. Boland, S. Thevelin, W. Knol et al., Development of a core outcome set for medication review in older patients with multimorbidity and polypharmacy: a study protocol, Clin Interventions Aging, vol.12, pp.1379-89, 2017.

J. Beuscart, L. G. Pont, S. Thevelin, B. Boland, O. Dalleur et al., A systematic review of the outcomes reported in trials of medication review in older patients: the need for a core outcome set, Br J Clin Pharmacol, vol.83, pp.942-52, 2017.

V. Der-gracht and H. A. , Consensus measurement in Delphi studies: Review and implications for future quality assurance, Technol Forecast Soc Change, vol.79, pp.1525-1561, 2012.

S. M. Matanovi? and V. Vlahovic-palcevski, Potentially inappropriate medications in the elderly: a comprehensive protocol, Eur J Clin Pharmacol, vol.68, pp.1123-1161, 2012.

C. Wong, Y. Ko, and A. Chan, Clinically significant drug-drug interactions between oral anticancer agents and nonanticancer agents: profiling and comparison of two drug compendia, Ann Pharmacother, vol.42, pp.1737-1785, 2008.

A. J. Forster, H. J. Murff, J. F. Peterson, T. K. Gandhi, and D. W. Bates, Adverse drug events occurring following hospital discharge, J Gen Intern Med, vol.20, pp.317-340, 2005.

K. E. Schmader, J. T. Hanlon, C. F. Pieper, R. Sloane, C. M. Ruby et al., Effects of geriatric evaluation and management on adverse drug reactions and suboptimal prescribing in the frail elderly, Am J Med, vol.116, pp.394-401, 2004.

E. Dragioti, B. Larsson, L. Bernfort, L. Å. Levin, and B. Gerdle, Prevalence of different pain categories based on pain spreading on the bodies of older adults in Sweden: a descriptive-level and multilevel association with demographics, comorbidities, medications, and certain lifestyle factors (PainS65+), J Pain Res, vol.9, pp.1131-1172, 2016.

K. V. Patel, E. A. Phelan, S. G. Leveille, S. E. Lamb, C. Missikpode et al., High prevalence of falls, fear of falling, and impaired balance in older adults with pain in the United States: findings from the 2011 National Health and Aging Trends Study, J Am Geriatr Soc, vol.62, pp.1844-52, 2014.

K. V. Patel, J. M. Guralnik, E. J. Dansie, and D. C. Turk, Prevalence and impact of pain among older adults in the United States: findings from the 2011 National Health and Aging Trends Study, Pain, vol.154, pp.2649-57, 2013.

T. Richards, V. M. Montori, F. Godlee, P. Lapsley, and D. Paul, Let the patient revolution begin, BMJ, vol.346, p.2614, 2013.