. Australia:-warwick, C. Butt, K. Delzoppo, and . Bain, Royal Children's Hospital

S. Erickson and N. Smalley, Princess Margaret Hospital for Children, Perth; Tavey Dorofaeff, Debbie Long (Royal Children's Hospital

N. Smalley and G. Wiseman,

J. Annick-de,

P. Demaret and M. Trippaerts,

, Ariane Willems, ShancyRooze (Hôpitaluniversitaire des enfantsReine Fabiola, Brussels

J. De-dooy, Canada: Elaine Gilfoyle, Lynette Wohlgemuth (Alberta Children's Hospital

M. Tucci and M. Dumitrascu,

D. Withington and J. Hickey, Montreal Children's Hospital

K. Choong and L. Sanders, McMaster Children's Hospital

G. Morrison,

J. Tijssen, Children's Hospital, London Health Sciences Centre

D. Wensley and G. Krahn, British Columbia Children's Hospital

M. Dugas and L. Gosselin,

M. Santschi, (. Chus, and . Sherbrooke, Chile: Bettina Von Dessauer, Nadia Ordenes (Hospital De Niños Roberto Del Río, Santiago), Nantes

N. Roullet-renoleau,

E. Javouhey and F. Cour-andlauer, Aurélie Portefaix (Hôpital Femme Mère Enfant, Hospices Civils de

O. Brissaud and J. Guichoux,

V. Payen,

P. Léger,

G. Mortamet, Hopital Necker

M. Maria,

A. Breining,

P. Tissieres, Hôpital Kremlin-Bicêtre

A. Dorkenoo,

, Greece: Filippia Nikolaou (Athens Children Hospital P&A Kyriakou, Athens). Italy: Anna Camporesi

F. Mario, Japan: Tatsuya Kawasaki, Shinya Miura (Shizuoka Children's Hospital

N. Zealand, :. Beca, M. Rea, C. Sherring, and T. Bushell, Norway: Gunnar Bentsen (Oslo University Hospital-Rikshospitalet, Oslo). Portugal: Alexandra Dinis (Hospital Pediátrico-CHUC

G. Pereira, UCIP Hospital Dona Estefânia

M. Vieira,

M. Moniz, Saudi Arabia: Saleh Alshehri (King Saud Medical City

M. Alasnag and A. Rajab, King Fahd Armed Forces Hospital, Jeddah), Spain: Iolanda Jordan (Hospital

J. Balcells,

A. Perez-ferrer, J. De, and V. Sánchez,

A. Martinez, Malaga

J. Lopez-herce and M. J. Solana,

J. González, Cadiz

M. T. and A. , Hospital Virgen del Rocío

M. Nieto and F. , Switzerland: Marie-Hélène Perez, Vivianne Amiet

C. Doell,

, The Netherlands: Suzan Cochius-den Otter, Berber Kapitein (Erasmus MC-Sophia Children's Hospital

M. Kneyber, Beatrix Children's Hospital, Groningen)

A. Kelleher,

B. Scholefield, A. Top, and N. Kelly, SatnamVirdee (Birmingham Children's Hospital

P. Davis and S. George, Bristol Royal Hospital for Children

C. Kay,

K. Hawkins and . Mccall, Victoria Brown (Royal Manchester Children's Hospital, Manchester)

K. Sykes,

R. Levin and I. Macleod, Hospital

M. Horan, PetrJirasek (Alder Hey Children's hospital, Liverpool

D. Inwald, A. Abdulla, and S. Raghunanan,

B. Taylor, Royal Belfast Hospital for Sick Children

A. Shefler and H. Sparkes, USA: Sheila Hanson, Katherine Woods, David Triscari, Kathy Murkowski (Children's Hospital of Wisconsin

M. Steiner, D. Nerheim, and A. Galster,

R. Higgerson and L. Christie, Dell Children's Medical Center

C. Philip, D. Spinella, L. Martin, and . Rourke,

J. Muszynski and L. Steele, Nationwide Children's Hospital

S. Ajizian and M. C. Mccrory,

O. Kevin, C. Brien, E. Babbitt, G. Felkel, and . Levine, Miller Children's Hospital Long Beach

E. J. Truemper and M. Zink, Children's Hospital and Medical Center

, Marianne Nellis (NYPH-Weill Cornell Medical College

N. J. Thomas, Debbie Spear (Penn State Hershey Children's Hospital

B. Markovitz, J. Terry, and R. Morzov, Children's Hospital Los Angeles

V. Montgomery, A. Michael, and M. Thomas,

M. Singleton and D. Jarvis, Sholeen Nett

D. Willson, Michelle Hoot (Virginia Commonwealth University

M. Bembea and A. Yiu,

D. Mckinley, E. Scarlett, J. Sankey, and M. Parikh,

E. and V. S. Faustino,

K. Michelson, J. Rilinger, and L. Campbell, Lurie Children's Hospital of Chicago

S. Gertz,

J. M. Cholette,

A. Jeyapalan, Holtz Children's Hospital-Jackson Memorial Hospital

S. Bateman and A. Johnson, UMass Memorial Children's Medical Center

E. Rivers, B. Nguyen, S. Havstad, J. Ressler, A. Muzzin et al., Early goal-directed therapy in the treatment of severe sepsis and septic shock, N Engl J Med, vol.345, issue.19, pp.1368-77, 2001.

N. D. Ferguson, D. J. Cook, G. H. Guyatt, S. Mehta, L. Hand et al., Highfrequency oscillation in early acute respiratory distress syndrome, N Engl J Med, vol.368, issue.9, pp.795-805, 2013.

D. Young, S. E. Lamb, S. Shah, I. Mackenzie, W. Tunnicliffe et al., Highfrequency oscillation for acute respiratory distress syndrome, N Engl J Med, vol.368, issue.9, pp.806-819, 2013.

P. Asfar, F. Meziani, J. F. Hamel, F. Grelon, B. Megarbane et al., High versus low blood-pressure target in patients with septic shock, N Engl J Med, vol.370, issue.17, pp.1583-93, 2014.

J. Lacroix, P. C. Hebert, D. A. Fergusson, A. Tinmouth, D. J. Cook et al., Age of transfused blood in critically ill adults, N Engl J Med, vol.372, issue.15, pp.1410-1418, 2015.
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M. M. Pollack, K. M. Patel, and U. E. Ruttimann, PRISM III: an updated pediatric risk of mortality score, Crit Care Med, vol.24, issue.5, pp.743-52, 1996.

S. Leteurtre, A. Martinot, A. Duhamel, F. Proulx, B. Grandbastien et al., Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study, Lancet, vol.362, issue.9379, pp.192-199, 2003.

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O. Karam, M. Tucci, C. Combescure, J. Lacroix, and P. C. Rimensberger, Plasma transfusion strategies for critically ill patients, Cochrane Database Syst Rev, issue.12, p.10654, 2013.

S. Raj, J. S. Killinger, J. A. Gonzalez, and L. Lopez, Myocardial dysfunction in pediatric septic shock, J Pediatr, vol.164, issue.1, pp.72-79, 2014.

C. N. Duncan, L. E. Lehmann, I. M. Cheifetz, K. Greathouse, A. E. Haight et al., Clinical outcomes of children receiving intensive cardiopulmonary support during hematopoietic stem cell transplant, Pediatr Crit Care Med, vol.14, issue.3, pp.261-268, 2013.

B. E. Orwoll, A. C. Spicer, M. S. Zinter, M. F. Alkhouli, R. G. Khemani et al., Elevated soluble thrombomodulin is associated with organ failure and mortality in children with acute respiratory distress syndrome (ARDS): a prospective observational cohort study, Crit Care, vol.19, p.435, 2015.

J. Rambaud, I. Guellec, P. L. Leger, S. Renolleau, and J. Guilbert, Venoarterial extracorporeal membrane oxygenation support for neonatal and pediatric refractory septic shock, Indian J Crit Care Med, vol.19, issue.10, pp.600-605, 2015.

H. Mtaweh, P. M. Kochanek, J. A. Carcillo, M. J. Bell, and E. L. Fink, Patterns of multiorgan dysfunction after pediatric drowning, Resuscitation, vol.90, pp.91-97, 2015.

E. T. Payne, X. Y. Zhao, H. Frndova, K. Mcbain, R. Sharma et al., Seizure burden is independently associated with short term outcome in critically ill children, Brain, vol.137, pp.1429-1467, 2014.

F. Shann, Are we doing a good job: PRISM, PIM and all that, Intensive Care Med, vol.28, issue.2, pp.105-112, 2002.

M. T. Keegan, O. Gajic, and B. Afessa, Severity of illness scoring systems in the intensive care unit, Crit Care Med, vol.39, issue.1, pp.163-172, 2011.

M. M. Pollack, R. Holubkov, T. Funai, J. M. Dean, J. T. Berger et al., The pediatric risk of mortality score: update 2015, Pediatr Crit Care Med, vol.17, issue.1, pp.2-9, 2016.

O. Karam, J. Lacroix, N. Robitaille, P. C. Rimensberger, and M. Tucci, Association between plasma transfusions and clinical outcome in critically ill children: a prospective observational study, Vox Sang, vol.104, issue.4, pp.342-351, 2013.

H. Khan, J. Belsher, M. Yilmaz, B. Afessa, J. L. Winters et al., Fresh-frozen plasma and platelet transfusions are associated with development of acute lung injury in critically ill medical patients, Chest, vol.131, issue.5, pp.1308-1322, 2007.

B. Sarani, W. J. Dunkman, L. Dean, S. Sonnad, J. I. Rohrbach et al., Transfusion of fresh frozen plasma in critically ill surgical patients is associated with an increased risk of infection, Crit Care Med, vol.36, issue.4, pp.1114-1122, 2008.

R. P. Barbaro, F. O. Odetola, K. M. Kidwell, M. L. Paden, R. H. Bartlett et al., Association of hospital-level volume of extracorporeal membrane oxygenation cases and mortality. Analysis of the extracorporeal life support organization registry, Am J Respir Crit Care Med, vol.191, issue.8, pp.894-901, 2015.

C. L. Bokman, J. Tashiro, E. A. Perez, D. S. Lasko, and J. E. Sola, Determinants of survival and resource utilization for pediatric extracorporeal membrane oxygenation in the United States 1997-2009, J Pediatr Surg, vol.50, issue.5, pp.809-823, 2015.

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