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, Onset to groin puncture, min, median (IQR)

, Abbreviations: ASPECTS=Alberta Stroke Program Early CT score

, ICA=internal carotid artery; IQR=interquartile range; IV=intravenous

, MCA=middle cerebral artery

, NIHSS=National Institutes of Health Stroke Scale; SBP=systolic blood pressure

, Model 1 indicated a linear logistic regression analysis and Model 2 indicated a non-linear (second order polynomial) logistic regression analysis. * logistic regression model stratified by center and adjusted for age, sex, history of hypertension and diabetes, baseline NIHSS, and prior use of thrombolysis. ?calculated after handling missing data on outcome, BP

, ? overall BP effect calculated using a likelihood ratio test comparing the model with and without linear and quadratic BP terms. Abbreviations: AIC= Akaike Information Criterion, BP=Blood pressure, CI=confidence intervals, NIHSS=National Institutes of Health Stroke Scale, p.2020