Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

One-Pot Synthesis of 2,5-Disubstituted Furans through In Situ Formation of Allenes and Enolization Cascade

Abstract : A one-pot synthesis of 2,5-disubstituted furans from γ-ketoacids is reported. In situ formation of allenoates by action of chloroformate on carboxylic acid following by enolization of ketone affords furan derivatives by cyclization. The reaction was extended to a wide scope of ketoacids and phosphonium salts. This methodology was applied on levulinic acid and derivatives, one of the biosourced platform chemicals.
Type de document :
Article dans une revue
Domaine :
Liste complète des métadonnées

https://hal.univ-lille.fr/hal-03246328
Contributeur : Lilloa Université de Lille <>
Soumis le : mercredi 2 juin 2021 - 12:19:39
Dernière modification le : jeudi 17 juin 2021 - 11:06:03

Identifiants

Collections

Citation

Yann Bernhard, Joachim Gilbert, Till Bousquet, Audrey Favrelle-Huret, Philippe Zinck, et al.. One-Pot Synthesis of 2,5-Disubstituted Furans through In Situ Formation of Allenes and Enolization Cascade. European Journal of Organic Chemistry, Wiley-VCH Verlag, 2019, European Journal of Organic Chemistry, 2019 (48), pp.7870-7873. ⟨10.1002/ejoc.201901669⟩. ⟨hal-03246328⟩

Partager

Métriques

Consultations de la notice

10