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Article Dans Une Revue Polycyclic Aromatic Compounds Année : 2022

An efficient synthesis of phthalimides and their biological activities

Hamida Jelali
  • Fonction : Auteur
Naceur Hamdi
  • Fonction : Auteur

Résumé

Practical and efficient synthesis of phthalimides compounds 3 were described and characterized. The synthesized compounds were screened for their antimicrobial activities against gram-positive bacterial strains (Micrococcus luteus, Listeria monocytogenes, Staphylococcus aureus and Bacillus cereus), a gram-negative bacterial strain (Salmonella typhimurium) and a fungus (Candida albicans). Cytotoxicity studies of the of phthalimides 3 were conducted in two human cancer cell lines, MDA-MB-231 and MCF-7.

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Dates et versions

hal-04303213 , version 1 (23-11-2023)

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Hamida Jelali, Lamjed Mansour, Eric Deniau, Mathieu Sauthier, Naceur Hamdi. An efficient synthesis of phthalimides and their biological activities. Polycyclic Aromatic Compounds, 2022, Polycyclic Aromatic Compounds, 42 (4), pp.1806-1813. ⟨10.1080/10406638.2020.1809468⟩. ⟨hal-04303213⟩
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