An efficient synthesis of phthalimides and their biological activities
Résumé
Practical and efficient synthesis of phthalimides compounds 3 were
described and characterized. The synthesized compounds were screened
for their antimicrobial activities against gram-positive bacterial strains
(Micrococcus luteus, Listeria monocytogenes, Staphylococcus aureus and
Bacillus cereus), a gram-negative bacterial strain (Salmonella typhimurium)
and a fungus (Candida albicans). Cytotoxicity studies of the of phthalimides
3 were conducted in two human cancer cell lines, MDA-MB-231 and MCF-7.