The objective of this study was to test the feasibility of automatically extracting and exploiting data from the YouTube platform, with a focus on the videos produced by the French YouTuber HugoDécrypte during COVID-19 quarantine in France. For this, we used the YouTube API, which allows the automatic collection of data and meta-data of videos. We have identified the main topics addressed in the comments of the videos and assessed their polarity. Our results provide insights on topics trends over the course of the quarantine and highlight users sentiment towards on-going events. The method can be expanded to large video sets to automatically analyse high amount of user-produced data.