Analytical documentation of an Arabian horse fatality related to Oenanthe crocata poisoning - Université de Lille Accéder directement au contenu
Article Dans Une Revue Toxicon Année : 2022

Analytical documentation of an Arabian horse fatality related to Oenanthe crocata poisoning

Résumé

Analytical detection of Oenanthe crocata toxins in biological samples is challenging because of their instability, the lack of commercially available standards and the exceptionally low detection of these molecules using mass spectrometry. This work aims to report the used analytical methods that allowed identification of the main plant toxins in biological samples from an equid (an Arabian horse) fatality related to hemlock water dropwort (Oenanthe crocata Linnaeus) intake. Using both LC-DAD and LC-HRMS methods allowed identification (i) of oenanthotoxin in roots found on the site, root fragments found in the stomach, stomach content, kidney, and liver, and (ii) of the hydrogenated metabolite of oenanthotoxin (2,3-dihydro-oenanthotoxin) in roots found on the site, root fragments found in the stomach, stomach content, kidney, liver and spleen. Reported analytical data about Oenanthe crocata toxins can be useful for identification of the ingested plant and for supporting a poisoning diagnosis in such cases.
Fichier principal
Vignette du fichier
Gish et al.pdf (1.47 Mo) Télécharger le fichier
Origine : Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04474615 , version 1 (23-02-2024)

Identifiants

Citer

Alexandr Gish, Cynthia Robveille, Thomas Gicquel, Delphine Allorge, Gilbert Gault, et al.. Analytical documentation of an Arabian horse fatality related to Oenanthe crocata poisoning. Toxicon, 2022, Toxicon, 210, pp.39-43. ⟨10.1016/j.toxicon.2022.02.009⟩. ⟨hal-04474615⟩
5 Consultations
1 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More