Opinion on the re-evaluation of mono- and diglycerides of fatty acids (E 471) as food additive in foods for infants below 16 weeks of age and follow-up of their re-evaluation as food additives for uses in foods for all population groups. - Université de Lille Accéder directement au contenu
Article Dans Une Revue EFSA Journal Année : 2021

Opinion on the re-evaluation of mono- and diglycerides of fatty acids (E 471) as food additive in foods for infants below 16 weeks of age and follow-up of their re-evaluation as food additives for uses in foods for all population groups.

M. Younes
  • Fonction : Auteur
G. Aquilina
  • Fonction : Auteur
L. Castle
  • Fonction : Auteur
K. H. Engel
  • Fonction : Auteur
P. Fowler
  • Fonction : Auteur
M. J. Frutos Fernandez
  • Fonction : Auteur
P. Fürst
  • Fonction : Auteur
R. Gürtler
  • Fonction : Auteur
T. Husøy
  • Fonction : Auteur
M. Manco
  • Fonction : Auteur
W. Mennes
  • Fonction : Auteur
P. Moldeus
  • Fonction : Auteur
S. Passamonti
  • Fonction : Auteur
R. Shah
  • Fonction : Auteur
I. Waalkens-Berendsen
  • Fonction : Auteur
D. Wölfle
  • Fonction : Auteur
M. Wright
  • Fonction : Auteur
B. Dusemund
  • Fonction : Auteur
A. Mortensen
  • Fonction : Auteur
S. Barmaz
  • Fonction : Auteur
A. Tard
  • Fonction : Auteur
G. Vianello
  • Fonction : Auteur
U. Gundert-Remy
  • Fonction : Auteur

Résumé

Mono- and diglycerides of fatty acids (E 471) was re-evaluated in 2017 by the former EFSA Panel onFood Additives and Nutrient sources added to Food (ANS). As a follow-up to this assessment, thePanel on Food Additives and Flavouring was requested to assess mono- and diglycerides of fatty acids(E 471) for its use as food additive in food for infants below 16 weeks of age belonging to foodcategories 13.1.1 (Infant formulae) and 13.1.5.1 (Dietary foods for infants for special medical purposesand special formulae for infants). In addition, the FAF Panel was requested to address the issuesalready identified during the re-evaluation of the food additive in 2017 when used in food for thegeneral population. The Panel considered that there is no indication of adverse effects from theavailable animal studies at the highest dose tested and from the post marketing data. A comparisonwas made between the daily exposure to the sum of mono- and di-acylglycerols from breast milk andthat resulting from the use of E 471 in the infant formula. The Panel noted that the resultingexposures are in the same order of magnitude. Overall, the Panel concluded that there is no reason fora safety concern when E 471 used as food additive in FC 13.1.1 and 13.1.5.1 and according to theAnnex III to Regulation (EC) No 1333/2008. The risk assessment for toxic elements and impuritiesclearly indicated the need to lower the current maximum limits for arsenic, lead, cadmium and mercuryand to include limits for glycidyl esters, 3-monochloropropane diol and erucic acid in the EUspecifications of E 471
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hal-04482652 , version 1 (28-02-2024)

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M. Younes, G. Aquilina, L. Castle, K. H. Engel, P. Fowler, et al.. Opinion on the re-evaluation of mono- and diglycerides of fatty acids (E 471) as food additive in foods for infants below 16 weeks of age and follow-up of their re-evaluation as food additives for uses in foods for all population groups.. EFSA Journal, 2021, EFSA Journal, 19, pp.e06885. ⟨10.2903/j.efsa.2021.6885⟩. ⟨hal-04482652⟩

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