In this paper, a novel attitude control method for nonlinear missile system is proposed, which combines backstepping technique with linear active disturbance rejection control (LADRC). Firstly, the nonlinear missile model is introduced and transformed into the standard state equation. The linear extended state observer (LESO) is used to estimate the unknown variables. Compared with PID control method, the homologous LADRC design ensures that the state variables of the closed-loop system converge to the reference state. The stability of LESO and LADRC is theoretically analyzed and proved. A large number of comparative simulations show the effectiveness of the method. The simulation results show that LADRC has better control performance than SMC and PID method.