Risk factors associated with shortened latency before delivery in outpatients managed for preterm prelabor rupture of membranes - Université de Lille Accéder directement au contenu
Article Dans Une Revue Acta Obstetricia et Gynecologica Scandinavica Année : 2022

Risk factors associated with shortened latency before delivery in outpatients managed for preterm prelabor rupture of membranes

Résumé

Introduction: Preterm prelabor rupture of membranes (PPROM) occurs in 3% of preg-nancies and is the main cause (~30%) of premature delivery. Home care seems to be a safe alternative for the management of patients with PPROM, who have a longer la-tency than those with PPROM managed with conventional hospitalization. We aimed to identify the risk factors associated with a shortened latency before delivery in women with PPROM managed as outpatients.Material and methods: The design was a retrospective cohort study and the setting was a Monocentric Tertiary centre (Lille University Hospital, France) from 2009 to 2018. All consecutive patients in home care after PPROM at 24–36 weeks were in-cluded. For the main outcome measure we calculated the latency ratio for each pa-tient as the ratio of the real latency period to the expected latency period, expressed as a percentage. The risk factors influencing this latency ratio were evaluated.Results: A total of 234 patients were managed at home after PPROM. Mean latency was 35.5 ± 20.7 days, corresponding to an 80% latency ratio. In 196 (83.8%) patients the length of home care was more than 7 days. A lower latency ratio was significantly associated with oligohydramnios (p< 0.001), gestational age at PPROM (p= 0.006), leukocyte count at PPROM more than 12× 109/L (p= 0.025), and C- reactive protein concentration more than 5 mg/L at 7 days after PPROM (p= 0.046). Cervical length was not associated with a lower latency ratio.Conclusions: Women with PPROM managed with home care are stable. The main risk factor associated with a reduced latency is oligohydramnios. Outpatients with oligohydramnios should be informed of the probability of a shortened latency period.
Fichier principal
Vignette du fichier
Acta Obstet Gynecol Scand - 2021 - Point - Risk factors associated with shortened latency before delivery in outpatients.pdf (459.27 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte

Dates et versions

hal-04514867 , version 1 (21-03-2024)

Licence

Paternité - Pas d'utilisation commerciale - Pas de modification

Identifiants

Citer

Florian Point, Louise Ghesquiere, Elodie Drumez, Celine Petit, Damien Subtil, et al.. Risk factors associated with shortened latency before delivery in outpatients managed for preterm prelabor rupture of membranes. Acta Obstetricia et Gynecologica Scandinavica, 2022, Acta Obstetricia et Gynecologica Scandinavica, 101 (1), p. 1-162. ⟨10.1111/aogs.14287⟩. ⟨hal-04514867⟩

Collections

UNIV-LILLE
0 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More