INDEPENDENT SUBMISSIONS Prehospital predictors for return of spontaneous circulation in traumatic cardiac arrest Benhamed, Axel MD, MSc; Canon, Valentine PhD; Mercier, Eric MD, MSc; Heidet, Matthieu MD, PhD; Gossiome, Amaury MD; Savary, Dominique MD, PhD; El Khoury, Carlos MD, PhD; Gueugniaud, Pierre-Yves MD, PhD; Hubert, Hervé MD, PhD; Tazarourte, Karim MD, PhD Author Information From the Hospices Civils de Lyon, Service d'accueil des Urgences-SAMU 69 (A.B., A.G., P.-Y.G., K.T.), Centre Hospitalier Universitaire Edouard Herriot, Lyon, France; Centre de Recherche du CHU de Québec-Université Laval (A.B., E.M.), Québec, QC, Canada; Département de Médecine d'urgence (A.B., E.M.), CHU de Québec-Université Laval, Québec, QC, Canada; Research On Healthcare Performance (RESHAPE) (A.B., C.E.K., K.T.), INSERM U1290, Université Claude Bernard Lyon 1, Lyon, Franc; French National Out-of-Hospital Cardiac Arrest Registry Research Group (V.C., P.-Y.G.), Registre Électronique des Arrêts Cardiaques, Lille, France; Univ. Lille, CHU Lille, ULR 2694-METRICS (V.C., H.H.): Évaluation des Technologies de Santé et des Pratiques Médicales, Lille, France; SAMU 94, Hôpitaux Universitaires Henri Mondor, Assistance Publique-Hôpitaux de Paris (AP-HP) (M.H.), Créteil, France; Service d'accueil des Urgences (D.S.), Centre Hospitalier Universitaire d'Angers, Angers, France; RESCUe-RESUVal Network (C.E.K.), Centre Hospitalier Lucien Hussel, Vienne, France; Service d'accueil des Urgences (C.E.K.), Centre Hospitalier Medipole, Villeurbanne, France. Submitted: September 7, 2021, Revised: October 29, 2021, Accepted: November 10, 2021, Published online: November 17, 2021. Supplemental digital content is available for this article. Direct URL citations appear in the printed text, and links to the digital files are provided in the HTML text of this article on the journal’s Web site (www.jtrauma.com). Address for reprints: Axel Benhamed, MD, MSc, Hospices Civils de Lyon, Service d'accueil des Urgences-SAMU 69, Centre Hospitalier Universitaire Edouard Herriot, 5 Place d'Arsonval, 69437 Lyon, France; email: axel.benhamed@chu-lyon.fr. Journal of Trauma and Acute Care Surgery 92(3):p 553-560, March 2022. | DOI: 10.1097/TA.0000000000003474 Buy SDC Infographic BACKGROUND Traumatic cardiac arrests (TCAs) are associated with high mortality and the majority of deaths occur at the prehospital scene. The aim of the present study was to assess, in a prehospital physician-led emergency medical system, the factors associated with sustained return of spontaneous circulation (ROSC) in TCA, including advanced life procedures. The secondary objectives were to assess factors associated with 30-day survival in TCA, evaluate neurological recovery in survivors, and describe the frequency of organ donation among patients experiencing a TCA. METHODS We conducted a retrospective study of all TCA patients included in the French nationwide cardiac arrest registry from July 2011 to November 2020. Multivariable logistic regression analysis was used to identify factors independently associated with ROSC. RESULTS A total of 120,045 out-of-hospital cardiac arrests were included in the registry, among which 4,922 TCA were eligible for analysis. Return of spontaneous circulation was sustained on-scene in 21.1% (n = 1,037) patients. Factors significantly associated with sustained ROSC were not-asystolic initial rhythms (pulseless electric activity (odds ratio [OR], 1.81; 95% confidence interval [CI], 1.40–2.35; p < 0.001), shockable rhythm (OR, 1.83; 95% CI, 1.12–2.98; p = 0.016), spontaneous activity (OR, 3.66; 95% CI, 2.70–4.96; p < 0.001), and gasping at the mobile medical team (MMT) arrival (OR, 1.40; 95% CI, 1.02–1.94; p = 0.042). The MMT interventions significantly associated with ROSC were as follows: intravenous fluid resuscitation (OR, 3.19; 95% CI, 2.69–3.78; p < 0.001), packed red cells transfusion (OR, 2.54; 95% CI, 1.84–3.51; p < 0.001), and external hemorrhage control (OR, 1.74; 95% CI, 1.31–2.30; p < 0.001). Among patients who survived (n = 67), neurological outcome at Day 30 was favorable (cerebral performance categories 1–2) in 72.2% cases (n = 39/54) and 1.4% (n = 67/4,855) of deceased patients donated one or more organ. CONCLUSION Sustained ROSC was frequently achieved in patients not in asystole at MMT arrival, and higher ROSC rates were achieved in patients benefiting from specific advanced life support interventions. Organ donation was somewhat possible in TCA patients undergoing on-scene resuscitation.