First-line treatment using high-flow nasal cannula for children with severe bronchiolitis: applicability and risk factors for failure - Université de Lille Accéder directement au contenu
Article Dans Une Revue Archives de Pédiatrie Année : 2018

First-line treatment using high-flow nasal cannula for children with severe bronchiolitis: applicability and risk factors for failure

Résumé

BACKGROUND: Viral bronchiolitis is the leading cause of hospitalization in children during the first 12 months of life. There is evidence to support the use of noninvasive ventilation in bronchiolitis. A recent respiratory management of bronchiolitis is the use of high-flow nasal cannula (HFNC) therapy. The primary objective of this study was to evaluate the use of HFNC as the first-line treatment for children with severe bronchiolitis and the secondary objective was to identify factors for HFNC therapy failure. METHODS: Observational prospective study in a pediatric intensive care unit (PICU), during two consecutive seasons (2013-2014 without recommendation and 2014-2015 with a study design suggesting HFNC as first-line treatment). The percentages of children treated with HFNC, nasal continuous or biphasic positive airway pressure (nCPAP/BiPAP) and invasive ventilation were compared. Associations between parameters recorded and HFCN therapy failure were established. RESULTS: The percentage of patients treated with HFNC at admission was higher during the second season (90%, n=55/61) than the first season (34%, n=14/41) (p<0.0001). In bivariate analysis, heart rate, pH, and pCO22 CONCLUSIONS: In our PICU, HFNC therapy for children with bronchiolitis can potentially decrease the use of nCPAP. In this study, the factor of failure was higher pCO22
Fichier non déposé

Dates et versions

hal-04581685 , version 1 (21-05-2024)

Identifiants

Citer

Camille Guillot, Claire Le Reun, Helene Behal, Julien Labreuche, Morgan Recher, et al.. First-line treatment using high-flow nasal cannula for children with severe bronchiolitis: applicability and risk factors for failure. Archives de Pédiatrie, 2018, Archives de Pédiatrie, 25, pp.213-218. ⟨10.1016/j.arcped.2018.01.003⟩. ⟨hal-04581685⟩

Collections

UNIV-LILLE
5 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Mastodon Facebook X LinkedIn More