Neuroimaging outcomes associated with mild cognitive impairment subtypes in Parkinson's disease: A systematic review. - Université de Lille
Article Dans Une Revue (Article De Synthèse) Parkinsonism & Related Disorders Année : 2022

Neuroimaging outcomes associated with mild cognitive impairment subtypes in Parkinson's disease: A systematic review.

Résumé

BackgroundMild cognitive impairment in Parkinson's disease (PD-MCI) is heterogenous and cognitive subtypes have been identified. However, the anatomo-functional bases of each subtype remain partly unknown.ObjectiveTo propose a description of the current literature on neuroimaging findings associated with cognitive subtypes of PD-MCI.MethodsPubMed/Medline, Embase, PsycINFO and the Cochrane Library databases were searched (until April 2021). Studies comparing PD-MCI cognitive subtypes with healthy controls (HC) and PD patients with normal cognition (PD-NC) on any neuroimaging outcome were included.ResultsTen studies met the inclusion criteria. Six used structural MRI methods, two functional MRI methods, one electroencephalography and five positron or single-photon emission tomography. Most studies (n = 8) determined PD-MCI subtypes based on memory impairment and two based on executive impairment. Compared with HC and/or PD-NC, brain modifications were found in PD patients (a) with amnestic MCI and, to a lesser extent, non-amnestic MCI in occipital, parietal and temporal regions, (b) with executive MCI in frontal and striatal regions and (c) with non-executive MCI in posterior cortical regions.ConclusionsVery few neuroimaging studies have considered cognitive heterogeneity that exists within PD-MCI, making it difficult to draw robust conclusions regarding brain modifications associated with specific subtypes. Given the promising potential of neuroimaging methods in both clinical practice and research, further studies are needed to overcome the limitations of the current literature.
Fichier principal
Vignette du fichier
S1353802022000396.pdf (4.29 Mo) Télécharger le fichier
Origine Fichiers produits par l'(les) auteur(s)

Dates et versions

hal-04604348 , version 1 (22-07-2024)

Licence

Identifiants

Citer

Quentin Devignes, Renaud Lopes, Kathy Dujardin. Neuroimaging outcomes associated with mild cognitive impairment subtypes in Parkinson's disease: A systematic review.. Parkinsonism & Related Disorders, 2022, Parkinsonism and Related Disorders, 95, pp.122-137. ⟨10.1016/j.parkreldis.2022.02.006⟩. ⟨hal-04604348⟩

Collections

UNIV-LILLE
13 Consultations
10 Téléchargements

Altmetric

Partager

More