The impact and future of artificial intelligence in medical genetics and molecular medicine: an ongoing revolution
Firat Ozcelik
(1)
,
Mehmet Sait Dundar
(2)
,
A. Baki Yildirim
(1)
,
Gary Henehan
(3)
,
Oscar Vicente
(4)
,
José A. Sánchez-Alcázar
(5)
,
Nuriye Gokce
(1)
,
Duygu T. Yildirim
(1)
,
Nurdeniz Nalbant Bingol
(6)
,
Dijana Plaseska Karanfilska
(7)
,
Matteo Bertelli
(8)
,
Lejla Pojskic
(9)
,
Mehmet Ercan
(1)
,
Miklos Kellermayer
(10)
,
Izem Olcay Sahin
(1)
,
Ole K. Greiner-Tollersrud
(11)
,
Busra Tan
(1)
,
Donald Martin
(12)
,
Robert Marks
(13)
,
Satya Prakash
(14)
,
Mustafa Yakubi
(1)
,
Tommaso Beccari
(15)
,
Ratnesh Lal
(16, 17)
,
Sehime G. Temel
(6)
,
Isabelle Fournier
(18)
,
M. Cerkez Ergoren
(19)
,
Adam Mechler
(20)
,
Michel Salzet
(18)
,
Michele Maffia
(21)
,
Dancho Danalev
(22)
,
Qun Sun
(23)
,
Lembit Nei
(24)
,
Daumantas Matulis
(25)
,
Dana Tapaloaga
(26)
,
Andres Janecke
(27)
,
James Bown
(28)
,
Karla Santa Cruz
(29)
,
Iza Radecka
(30)
,
Celal Ozturk
(1)
,
Ozkan Ufuk Nalbantoglu
(1)
,
Sebnem Ozemri Sag
(6)
,
Kisung Ko
(31)
,
Reynir Arngrimsson
(32)
,
Isabel Belo
(33)
,
Hilal Akalin
(1)
,
Munis Dundar
(1)
1
Erciyes University
2 AGU - Abdullah Gul University [Kayseri, Turkey]
3 TU - Technological University [Dublin]
4 COMAV - Institute for Conservation & Improvement of Valentian Agrodiversity
5 ISCIII - Instituto de Salud Carlos III [Madrid]
6 Bursa Uludağ Üniversitesi
7 MASA - Macedonian Academy of Sciences and Arts [Skopje, North Macedonia]
8 Magi's Lab
9 UNIVERSITY OF SARAJEVO - UNIVERZITET U SARAJEVU
10 Semmelweis University [Budapest]
11 UiT - The Arctic University of Norway [Tromsø, Norway]
12 TIMC - Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525
13 BGU - Ben-Gurion University of the Negev
14 McGill University = Université McGill [Montréal, Canada]
15 UNIPG - Università degli Studi di Perugia = University of Perugia
16 UC Santa Barbara - University of California [Santa Barbara]
17 UC San Diego - University of California [San Diego]
18 PRISM - Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192
19 Near East University
20 La Trobe University
21 Università del Salento = University of Salento [Lecce]
22 University of Chemical Technology and Metallurgy [Sophia]
23 SCU - Sichuan University [Chengdu]
24 University of Tartu
25 Vilnius University [Vilnius]
26 UniBuc - University of Bucharest
27 IMU - Innsbruck Medical University = Medizinische Universität Innsbruck
28 Abertay University - Abertay University
29 USON - Universidad de Sonora
30 University of Wolverhampton
31 Chung-Ang University [Seoul]
32 University of Iceland [Reykjavik]
33 Universidade do Minho = University of Minho [Braga]
2 AGU - Abdullah Gul University [Kayseri, Turkey]
3 TU - Technological University [Dublin]
4 COMAV - Institute for Conservation & Improvement of Valentian Agrodiversity
5 ISCIII - Instituto de Salud Carlos III [Madrid]
6 Bursa Uludağ Üniversitesi
7 MASA - Macedonian Academy of Sciences and Arts [Skopje, North Macedonia]
8 Magi's Lab
9 UNIVERSITY OF SARAJEVO - UNIVERZITET U SARAJEVU
10 Semmelweis University [Budapest]
11 UiT - The Arctic University of Norway [Tromsø, Norway]
12 TIMC - Translational Innovation in Medicine and Complexity / Recherche Translationnelle et Innovation en Médecine et Complexité - UMR 5525
13 BGU - Ben-Gurion University of the Negev
14 McGill University = Université McGill [Montréal, Canada]
15 UNIPG - Università degli Studi di Perugia = University of Perugia
16 UC Santa Barbara - University of California [Santa Barbara]
17 UC San Diego - University of California [San Diego]
18 PRISM - Protéomique, Réponse Inflammatoire, Spectrométrie de Masse (PRISM) - U 1192
19 Near East University
20 La Trobe University
21 Università del Salento = University of Salento [Lecce]
22 University of Chemical Technology and Metallurgy [Sophia]
23 SCU - Sichuan University [Chengdu]
24 University of Tartu
25 Vilnius University [Vilnius]
26 UniBuc - University of Bucharest
27 IMU - Innsbruck Medical University = Medizinische Universität Innsbruck
28 Abertay University - Abertay University
29 USON - Universidad de Sonora
30 University of Wolverhampton
31 Chung-Ang University [Seoul]
32 University of Iceland [Reykjavik]
33 Universidade do Minho = University of Minho [Braga]
Isabelle Fournier
- Fonction : Auteur
- PersonId : 173955
- IdHAL : isabelle-fournier
- ORCID : 0000-0003-1096-5044
- IdRef : 137267029
Michel Salzet
- Fonction : Auteur
- PersonId : 1299890
- IdHAL : michel-salzet
Résumé
Artificial intelligence (AI) platforms have emerged as pivotal tools in genetics and molecular medicine, as in many other fields. The growth in patient data, identification of new diseases and phenotypes, discovery of new intracellular pathways, availability of greater sets of omics data, and the need to continuously analyse them have led to the development of new AI platforms. AI continues to weave its way into the fabric of genetics with the potential to unlock new discoveries and enhance patient care. This technology is setting the stage for breakthroughs across various domains, including dysmorphology, rare hereditary diseases, cancers, clinical microbiomics, the investigation of zoonotic diseases, omics studies in all medical disciplines. AI’s role in facilitating a deeper understanding of these areas heralds a new era of personalised medicine, where treatments and diagnoses are tailored to the individual’s molecular features, offering a more precise approach to combating genetic or acquired disorders. The significance of these AI platforms is growing as they assist healthcare professionals in the diagnostic and treatment processes, marking a pivotal shift towards more informed, efficient, and effective medical practice. In this review, we will explore the range of AI tools available and show how they have become vital in various sectors of genomic research supporting clinical decisions.