Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Development of chiral C2-symmetric N-heterocyclic carbene Rh(I) catalysts through control of their steric properties

Abstract : Chiral square-planar Rh(I) complexes based on new C2-symmetric NHC ligands have been synthesized selectively in a few steps as single diastereoisomers. These chiral pre-catalysts were applied to the asymmetric transfer hydrogenation of 1-phe-nylpropanone and to the 1,2-addition of arylboronic acids to aldehydes. We demonstrated a proper functionalization of the aromatic rings connected to the nitrogen atoms of the NHC ligand improved significantly the asymmetric induction of the chiral Rh(I) NHC catalysts. Bulky substituents allowed a better control of the steric features of the catalyst quadrants because they behaved as confor-mational and chirality relays of the NHC chiral backbone.
Type de document :
Article dans une revue
Liste complète des métadonnées

Littérature citée [32 références]  Voir  Masquer  Télécharger

https://hal.univ-lille.fr/hal-02309206
Contributeur : Lilloa Université de Lille <>
Soumis le : lundi 31 août 2020 - 15:13:20
Dernière modification le : vendredi 16 octobre 2020 - 11:22:06

Fichier

Manuscript_ hal-02309206, v1.p...
Fichiers produits par l'(les) auteur(s)

Identifiants

Collections

Citation

Marc-Antoine Abadie, Kirsty Macintyre, Cédric Boulho, Peter Hoggan, Frederic Capet, et al.. Development of chiral C2-symmetric N-heterocyclic carbene Rh(I) catalysts through control of their steric properties. Organometallics, American Chemical Society, 2019, 38 (2), pp.536-543. ⟨10.1021/acs.organomet.8b00823⟩. ⟨hal-02309206⟩

Partager

Métriques

Consultations de la notice

78

Téléchargements de fichiers

27