The 1-minute sit-to-stand test to detect exercise-induced oxygen desaturation in patients with interstitial lung disease - Université de Lille Accéder directement au contenu
Article Dans Une Revue Therapeutic Advances in Respiratory Disease Année : 2018

The 1-minute sit-to-stand test to detect exercise-induced oxygen desaturation in patients with interstitial lung disease

Résumé

BACKGROUND: Although the 6-min walk test (6MWT) is the gold standard for assessing exercise-induced impairment of gas exchange, it cannot easily be performed in a clinical office environment. The aim of this study was to compare the 1-min sit-to-stand test (1STST) with the 6MWT for the ability to assess exercise-induced oxygen desaturation in patients with interstitial lung diseases (ILDs). METHODS: A total of 107 patients were enrolled and classified into three groups: sarcoidosis, fibrotic idiopathic interstitial pneumonia (f-IIP), and other forms of ILD. The 6MWT and 1STST were performed on the same day, and pulmonary function tests, pulse oxygen saturation (SpO2), and dyspnea and fatigue (modified Borg scale) were assessed. SpO2 desaturation was evaluated by intraclass correlation coefficient (ICC), Bland-Altman analysis, and kappa (κ) coefficient in the whole population and the patient subgroups. RESULTS: The SpO2 nadir during the 1STST and 6MWT showed good consistency [mean ± standard deviation: 92.5% ± 5% and 90% ± 7%, respectively; ICC 0.77, 95% confidence interval (CI) 0.71-0.83] and correlated strongly ( r = 0.9, p < 0.0001). The frequency of patients with oxygen desaturation ⩾4% was also consistent for the two exercise tests ( κ = 0.68, 95% CI 0.54-0.82). The number of repetitions in the 1STST correlated with the 6MWT distance ( r = 0.5, p < 0.0001), but the dyspnea scores were higher during the 1STST than the 6MWT ( p < 0.0001). These findings did not differ for the three patient subgroups. CONCLUSION: The 1STST can measure exercise-induced desaturation in ILD patients and could be used as an alternative test to the 6MWT in office practice.
Fichier principal
Vignette du fichier
The 1-minute sit-to-stand test.pdf (184.54 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-02519548 , version 1 (26-03-2020)

Licence

Paternité - Pas d'utilisation commerciale

Identifiants

Citer

Justine Briand, Helene Behal, Cecile Chenivesse, Lidwine Wemeau-Stervinou, Benoit Wallaert. The 1-minute sit-to-stand test to detect exercise-induced oxygen desaturation in patients with interstitial lung disease. Therapeutic Advances in Respiratory Disease, 2018, 12, pp.1753466618793028. ⟨10.1177/1753466618793028⟩. ⟨hal-02519548⟩

Collections

INSERM UNIV-LILLE
57 Consultations
74 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More