The present study focuses on painting perception during the visit of a museum and aims at evaluating how a portable technological interface may improve young children’s perceptual experience in the museum. A tablet-based educational platform targeting young public have been designed for a museum (Museo+, Palais des Beaux Arts de Lille) in accordance with Design for All recommendations. Physiological (electrodermal activity) and eye tracking data from 2 subjects were collected during a museum visit mediated by the mobile device Museo+. Results showed that children behave differently but each one has manifested some interest for the visit. Moreover, our methodology allowed us to obtain objective data concerning the usability of the application and detect which in-game events triggered arousal and engagement.