Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Synthesis of levulinic acid based poly(amine-co-ester)s

Abstract : Four novel biobased monomers (i.e. two diesters and two hydroxyesters) bearing a tertiary amine in their backbone have been synthesized from the sustainable methyl levulinate and amino-alcohols/amino-esters derived from natural amino acids. Their homopolymerization/copolymerization with diols leads to six poly(amine-co-ester)s with various microstructures. These families of biodegradable polyesters have been reported to be efficient carriers for gene delivery. The polymers are carefully characterized by nuclear magnetic resonance spectroscopy (1H and 13C NMR) and size exclusion chromatography (SEC), and exhibit molecular weights (Mn) up to 36 kg mol−1 and dispersities (Đ) between 1.5 and 2.1. They also present good solubility in aqueous acidic media due to amine protonation. Such properties are promising for applications in the biomedical field or in personal care products.
Type de document :
Article dans une revue
Domaine :
Liste complète des métadonnées

https://hal.univ-lille.fr/hal-02976763
Contributeur : Philippe Zinck <>
Soumis le : jeudi 24 juin 2021 - 11:08:23
Dernière modification le : jeudi 8 juillet 2021 - 09:52:03

Licence


Distributed under a Creative Commons Paternité 4.0 International License

Identifiants

Collections

Citation

Yann Bernhard, Lucas Pagies, Sylvain Pellegrini, Till Bousquet, Audrey Favrelle, et al.. Synthesis of levulinic acid based poly(amine-co-ester)s. Green Chemistry, Royal Society of Chemistry, 2019, 21, pp.123-128. ⟨10.1039/C8GC03264E⟩. ⟨hal-02976763v2⟩

Partager

Métriques

Consultations de la notice

13

Téléchargements de fichiers

17