Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes of Indenoisoquinoline Derivatives - Université de Lille
Article Dans Une Revue Organometallics Année : 2016

Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes of Indenoisoquinoline Derivatives

Nathalie Wambang
  • Fonction : Auteur

Résumé

Novel ruthenium complexes of indenoisoquinoline derivatives were synthesized and characterized. The structure of the complex 9 was determined by single-crystal X-ray crystallography. Ruthenium complexes displayed strong DNA interactions. The cytotoxic activity of the complexes was tested against five cancer cell lines (MDA-MB-231, MCF-7, HEK-293, HT-29, and DU-145).
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Dates et versions

hal-03033340 , version 1 (03-11-2023)

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Nathalie Wambang, Nadege Schifano, Alain Martoriati, Natacha Henry, Brigitte Baldeyrou, et al.. Synthesis, Structure, and Antiproliferative Activity of Ruthenium(II) Arene Complexes of Indenoisoquinoline Derivatives. Organometallics, 2016, Organometallics, 35 (17), pp.2868-2872. ⟨10.1021/acs.organomet.6b00440⟩. ⟨hal-03033340⟩
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