LaFe1−xCuxO3 and La2CuO4 catalysts are investigated for three-way-catalysis application. LaFe1−xCuxO3 solids present interesting catalytic properties mainly with respect to hydrocarbon and CO oxidation and NO reduction in rich conditions with high N2 selectivity. The partial substitution of iron with copper leads to enhanced catalytic activity for oxidation reactions. This can be attributed to the higher reducibility of the solid as evidenced earlier by H2-temperature-programmed reduction. The orthorhombic structure associated with LaFe1−xCuxO3 solids (x up to 0.2) revealed good thermal stability during catalytic cycles in stoichiometric, lean and rich conditions whereas the Ruddlesden Popper phase associated with La2CuO4 completely decomposed in rich conditions.