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Article dans une revue

Definition of Personalized Medicine and Targeted Therapies: Does Medical Familiarity Matter?

Abstract : Personalized medicine (PM) is increasingly becoming a topic of discussion in public health policies and media. However, there is no consensus among definitions of PM in the scientific literature and the terms used to designate it, with some definitions emphasizing patient-centered aspects and others emphasizing biomedical aspects. Furthermore, terms used to refer to PM (e.g., “pharmacogenomics” or, more often, “targeted therapies”) are diverse and differently used. To our knowledge, no study has apprehended the differences of definition and attitudes toward personalized medicine and targeted therapies according to level of familiarity with the medical field. Our cohort included 349 French students from three different academic fields, which modulated their familiarity level with the medical field. They were asked to associate words either to “personalized medicine” or “target therapies”. Then, they were asked to give an emotional valence to their associations. Results showed that nonfamiliar students perceived PM as more positive than targeted therapies (TT), whereas familiar students showed no difference. Only familiar students defined PM and TT with technical aspects such as genetics or immunology. Further studies are needed in the field in order to determine which other factors could influence the definitions of PM and TT and determine how these definitions could have an impact in a clinical setting.
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Soumis le : lundi 12 avril 2021 - 11:56:06
Dernière modification le : mardi 13 avril 2021 - 03:10:11
Archivage à long terme le : : mardi 13 juillet 2021 - 18:40:51


Fournier et al. (2021) - Defin...
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Valentyn Fournier, Thomas Prebet, Alexandra Dormal, Maite Brunel, Robin Cremer, et al.. Definition of Personalized Medicine and Targeted Therapies: Does Medical Familiarity Matter?. Journal of Personalized Medicine, MDPI, 2021, 11 (1), pp.26. ⟨10.3390/jpm11010026⟩. ⟨hal-03195949⟩



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