Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infections

Abstract : The emergence of the novel coronavirus SARS-CoV-2, which causes severe respiratory tract infections in humans (COVID-19), has become a global health concern. One of the most worrying features of COVID-19 is a phenomenon known as the “cytokine storm”, which is a rapid overreaction of the immune system. Additionally, coagulation abnormalities, thrombocytopenia and digestive symptoms, including anorexia, vomiting, and diarrhea, are often observed in critically ill patients with COVID-19. Baker’s yeast β-glucan, a natural immunomodulatory component derived from Saccharomyces cerevisiae, primes the immune system to respond better to any microbial infection. Our previous studies have shown that oral administration of yeast β-glucans decreased the diarrhoea, modulated cytokine expression, and reduced the intestinal inflammation. Additionally, we showed that β-glucan fractions decreased coagulation in plasma and reduced the activation of platelets. During the period of home confinement facing individuals during the COVID-19 pandemic, our immune defence could be weakened by different factors, including stress, anxiety and poor nutrition, while a healthy diet rich in vitamins C and D can reinforce the immune defence and reduce the risk of microbial infections. Additionally, β-glucan can be used to strengthen the immune defence in healthy individuals prior to any possible viral infections. This short review focuses on the role of baker’s yeast β-glucan, with a healthy diet rich in natural vitamins C and D, in addition to a healthy gut microbiota can provide synergistic immune system support, helping the body to naturally defend prior to respiratory virus infections, until stronger options such as vaccines are available.
Liste complète des métadonnées

https://hal.univ-lille.fr/hal-03325643
Contributeur : Lilloa Université de Lille <>
Soumis le : mercredi 25 août 2021 - 10:18:45
Dernière modification le : jeudi 26 août 2021 - 03:30:03

Fichier

s13099-020-00385-2.pdf
Fichiers éditeurs autorisés sur une archive ouverte

Licence


Distributed under a Creative Commons Paternité 4.0 International License

Identifiants

Collections

Citation

Samir Jawhara. How to boost the immune defence prior to respiratory virus infections with the special focus on coronavirus infections. Gut Pathogens, BioMed Central, 2020, 12, pp.47. ⟨10.1186/s13099-020-00385-2⟩. ⟨hal-03325643⟩

Partager

Métriques

Consultations de la notice

11

Téléchargements de fichiers

8