Cyclic Ethers (CEs) belong to a class of compounds of importance to understand the chemistry of both the auto-ignition of hydrocarbon fuels and the combustion of oxygenated biofuels. Our recent review article, which is under revision process, aims at systematically analyzing the application of up-to-date methods to unveil the gas-phase oxidation chemistry of these compounds and analyzing our knowledge on the formation and consumption chemistry of these compounds. In the present presentation, some selected examples concerning the chemistry of CE high-temperature degradation with enlightening the specific experimental and modeling features of the involved reactions are presented and discussed.