This handbook provides a thorough introduction to the economics and sociology of conventions (EC/SC). With its origins in French structuralism and sociological pragmatism, EC/SC is a heterodox approach which focuses on the study of economic conventions as socio-cultural frames through which economic actors must coordinate, interpret, and evaluate their actions. Intrinsically interdisciplinary, EC/SC has a range of applications from economics, statistics, economic sociology, educational sociology, the analysis of different kinds of markets, the study of culture, politics, law, geography, history, the political economy of health, agricultural economics, to urban studies and many others. This approach integrates the experience of many scientific fields and combines a full range of quantitative and qualitative methods that would otherwise be separated in traditional analysis. This handbook presents the concepts, methodologies, studies and achievements of EC/SC for an international and multidisciplinary readership, gathering contributions from a diverse panel of leading institutionalist scholars. This handbook is appropriate for students and researchers interested in learning more about this transdisciplinary practice in institutional analysis.