Fighting Enteroviral Infections to Prevent Type 1 Diabetes. - Université de Lille
Article Dans Une Revue Microorganisms Année : 2022

Fighting Enteroviral Infections to Prevent Type 1 Diabetes.

Résumé

Enteroviruses (EVs), especially coxsackieviruses B (CVB), are believed to trigger or accelerate islet autoimmunity in genetically susceptible individuals that results in type 1 diabetes (T1D). Therefore, strategies are needed to fight against EV infections. There are no approved antiviral drugs currently available, but various antiviral drugs targeting viral or host cell proteins and vaccines have recently shown potential to combat CVB infections and may be used as new therapeutic strategies to prevent or reduce the risk of T1D and/or preserve β-cell function among patients with islet autoantibodies or T1D.

Domaines

Vaccinologie
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Dates et versions

hal-04454365 , version 1 (13-02-2024)

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Magloire Pandoua Nekoua, Ambroise Mercier, Abdulaziz Alhazmi, Famara Sane, Enagnon Kazali Alidjinou, et al.. Fighting Enteroviral Infections to Prevent Type 1 Diabetes.. Microorganisms, 2022, Microorganisms, 10, pp.768. ⟨10.3390/microorganisms10040768⟩. ⟨hal-04454365⟩

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