Status of indoleamine-2,3-dioxygenase 1 in infiltrating ductal carcinoma of breast cancer: a new prognostic indicator for aggressive tumors
Résumé
The tryptophan pathway has been demonstrated to be involved in tumor
progression. Increased expression of indoleamine 2,3-dioxygenases has been observed in several human
tumors types, such as breast cancer. In order to study the role of IDO expression as a prognostic
marker, the serum tryptophan and kynurenine concentrations and the ratio of kynurenine to tryptophan
(K/T) of 165 subjects were compared, and correlations were established.
Domaines
Sciences du Vivant [q-bio]| Origine | Fichiers éditeurs autorisés sur une archive ouverte |
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