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Article Dans Une Revue Journal of Clinical Hypertension Année : 2021

Prevalence of hypertensive disorders during pregnancy in France (2010-2018): The nationwide CONCEPTION study

Résumé

Hypertensive disorders of pregnancy (HDP) are one of the leading causes of mater-nal and fetal morbidity and mortality. We aimed to estimate the prevalence of each HDP in France and to study their associations. All pregnant women who delivered in France between 2010 and 2018 were included in a cohort and followed during their pregnancy and 6 weeks of postpartum. Each HDP occurring during the follow-up was identified. Prevalence of each HDP and cumulative incidence by gestational age were estimated. Incidence rate ratio (IRR) and 95% confidence interval (CI) for preeclamp-sia among women with preexisting or gestational hypertension (GH) were estimated using Poisson regression and adjusted for age were estimated. Between 2010 and 2018, 6 302 810 deliveries were included. HDP complicated 7.4% of pregnancies. Preeclampsia and GH complicated 2.0% and 4.2% of pregnancies, respectively. Most of preeclampsia cases occurred without a prior HDP. HELLP syndrome represented 10.4% of preeclampsia cases. Compared to nulliparous pregnancies without HDP prior preeclampsia, the age-adjusted IRR of preeclampsia was 6.2 [95% CI: 6.1-6.4] in nulliparous pregnancies with preexisting hypertension and 2.9 [95% CI: 2.8-3.0] in nulliparous pregnancies with GH. In France, HDP occurred in 7.4% of all pregnan-cies. Women with preexisting chronic hypertension are at high risk to present preec-lampsia during pregnancy. Preeclampsia complicated 2.0% of pregnancies in France. Tailoring management of women according to the HDP is a major challenge to avoid complications related to these disorders.
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hal-04502809 , version 1 (13-03-2024)

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V. Olie, E. Moutengou, C. Grave, C. Deneux-Tharaux, N. Regnault, et al.. Prevalence of hypertensive disorders during pregnancy in France (2010-2018): The nationwide CONCEPTION study. Journal of Clinical Hypertension, 2021, The Journal of Clinical Hypertension, 23 (7), pp.P. 1273-1456. ⟨10.1111/jch.14254⟩. ⟨hal-04502809⟩
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