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Article Dans Une Revue Allergy Année : 2020

Human airway epithelial cells express a functional IL-5 receptor.

Résumé

We found that HBEC expressed the IL-5 receptor, which triggered intracellular signaling and changed gene expression. This data indicate that in addition to targeting eosinophils, IL-5 and anti-IL-5 biologics may have a direct role on AEC.

Dates et versions

hal-04585154 , version 1 (23-05-2024)

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Karina T Barretto, Rebecca A Brockman-Schneider, Ine Kuipers, Sarmila Basnet, Yury A Bochkov, et al.. Human airway epithelial cells express a functional IL-5 receptor.. Allergy, 2020, Allergy, 75, pp.2127-2130. ⟨10.1111/all.14297⟩. ⟨hal-04585154⟩

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