We report novel oxide glasses that are compatible with ultra-high Young's modulus (∼150 GPa) and a small coefficient of thermal expansion (∼5.0 ppm/K). These glasses were prepared using a conventional melt-quenching technique. The viscosity–temperature relation provides the reshaping temperature for the stiff and less dilated oxide glasses. The origin of the ultra-high Young's modulus is the inclusion of Y2O3 as well as five- and six-coordinated alumina oxide and Ta2O5, which has a large ionic packing ratio due to higher oxygen coordination numbers. On the other hand, the small thermal expansion coefficient originates from including Ta2O5 and SiO2 with large dissociation energy due to strong bonds.