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Neurogliovascular unit after cerebral ischemia: Is the vascular wall a pharmacological target
Abstract : Ischemic stroke induces drastic alterations of the functions of the neurogliovascular unit with dramatic consequences on the well-being of the patients in terms of cognitive and motor handicap. Nowadays, only very few therapeutics are available as a treatment of ischemic stroke. Ischemia is a multifactorial pathology involving different cerebral cellular components such as neurons, astrocytes and vessels working as a functional unit. Recent experimental strategy investigation involving different agents with antioxidant properties (dt-BC, stobadine) or pleiotropic effects (lipopolysaccharide, LPS) has been developed to evaluate whether the vascular wall could be considered as a potential target in neuroprotection concept.
https://hal.univ-lille.fr/hal-02477189
Contributeur : Lilloa Université de Lille <>
Soumis le : jeudi 13 février 2020 - 11:26:26
Dernière modification le : jeudi 13 février 2020 - 11:26:28
Contributeur : Lilloa Université de Lille <>
Soumis le : jeudi 13 février 2020 - 11:26:26
Dernière modification le : jeudi 13 février 2020 - 11:26:28