Neurogliovascular unit after cerebral ischemia: Is the vascular wall a pharmacological target - Université de Lille Accéder directement au contenu
Article Dans Une Revue Psychoneuroendocrinology Année : 2007

Neurogliovascular unit after cerebral ischemia: Is the vascular wall a pharmacological target

Résumé

Ischemic stroke induces drastic alterations of the functions of the neurogliovascular unit with dramatic consequences on the well-being of the patients in terms of cognitive and motor handicap. Nowadays, only very few therapeutics are available as a treatment of ischemic stroke. Ischemia is a multifactorial pathology involving different cerebral cellular components such as neurons, astrocytes and vessels working as a functional unit. Recent experimental strategy investigation involving different agents with antioxidant properties (dt-BC, stobadine) or pleiotropic effects (lipopolysaccharide, LPS) has been developed to evaluate whether the vascular wall could be considered as a potential target in neuroprotection concept.

Dates et versions

hal-02477189 , version 1 (13-02-2020)

Identifiants

Citer

Michele Bastide, Thavarak Ouk, F. Plaisier, Olivier Petrault, Svorad Stolc, et al.. Neurogliovascular unit after cerebral ischemia: Is the vascular wall a pharmacological target. Psychoneuroendocrinology, 2007, Psychoneuroendocrinology, 32 (Suppl 1), pp.S36-S39. ⟨10.1016/j.psyneuen.2007.03.015⟩. ⟨hal-02477189⟩

Collections

UNIV-LILLE
18 Consultations
0 Téléchargements

Altmetric

Partager

Gmail Facebook X LinkedIn More